How about text to speech and speech recognition and how games could be made more fun through the use of it.[/quote:233041a5ab]
Personally I would just take the big picture and extend this to the whole problem of GUI, and how it has evolved throughout the years.
VR/Text to speech is but one element of a bigger jigsaw, that some people have solved admirably well, but only partially, over the years.
VR is just one way that you could improve interfaces, and sometimes a good menu system would actually be much better than a bad VR interface.