Immature production practices are a major hurdle for the industry. Too many developers shy away from learning things like User Interface Design because they claim that art can’t be managed – basically just an excuse for being lazy.
The film industry manages to be creative while understanding that there are rules for the use of lighting, cameras etc which, if understood, will improve your ability to convey your message. Developers are constantly releasing games with crappy 3rd person cameras which damage the game-play experience when such problems were solved years ago.
Managing your asset pipeline and planning for multi-format, multi-language development are other key issues that developers forget in the rush to make a game and its something more and more publishers are picking up on. Many make a review of your production pipeline a key part of their due diligence.